Can we take the STING out of bone loss? Pathway presents potential treatment target for skeletal aging

As we age, our bones go anemic and brittle, a process called osteoporosis. This bony nonaccomplishment is caused by changes successful the cells wrong the bony marrow microenvironment, specified arsenic elevated abdominous and inflammation-promoting immune cells. One molecular operator of inflammation is the STING signaling pathway, though the relation of this pathway successful aging bones has until present been unclear.