Deleting two molecular gatekeepers sharply reduces metastasis in mouse tumors

By analyzing idiosyncratic crab cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing epithelial-to-mesenchymal modulation (EMT) successful tumors and identified cardinal maestro regulators that power metastasis, revealing imaginable therapeutic vulnerabilities to artifact metastatic dissemination.