Beyond antibiotics—a paradigm shift toward bacteria-control-centric therapies

Antimicrobial absorption is 1 of the world's astir alarming nationalist wellness challenges due to the fact that multidrug-resistant (MDR) gram-negative bacteria progressively render adjacent last-line antibiotics ineffective, starring to substantially higher mortality rates. Polymyxins are a people of antibiotics that stay among the fewer attraction options disposable for terrible infections caused by resistant Escherichia coli. But their wide usage is constricted by superior broadside effects, including kidney and nervus toxicity.