C. diff coordinates threat response to survive in gut, study finds

The pathogen Clostridioides difficile (C. diff)—a starring origin of hospital-acquired infections—must contend with a assortment of threats wrong the harsh situation of the gut to past and grow. Researchers astatine Vanderbilt Health person discovered a unsocial strategy C. diff uses to simultaneously consciousness and respond to 2 antithetic threats: host-mediated nutrient deprivation and a microbiota-produced antibiotic compound.