Damaged red blood cells can trigger inflammation

When reddish humor cells interruption down, they merchandise heme, a constituent of hemoglobin that tin lend to inflammation and harm tissues and humor vessels. Researchers astatine Lund University person identified a mechanics by which heme activates an inflammatory absorption successful the blood. They besides were capable to artifact this pathway successful experimental models. The findings could person implications for diseases and conditions involving extended breakdown of reddish humor cells, including hemolytic uremic syndrome and malaria.