How blood vessels distinguish between growth and inflammation

The angiopoietin-Tie signaling pathway has agelong been known to beryllium indispensable for the maturation and attraction of steadfast humor vessels. It stabilizes the vas partition and regulates vascular maturation during development. At the aforesaid time, it plays an important relation successful inflammation, erstwhile humor vessels go activated and immune cells permission the bloodstream and participate the surrounding tissue. How the aforesaid signaling pathway tin power specified antithetic biologic functions has remained unclear.