How losing the 'guardian of the genome' can damage DNA and drive cancer

A caller survey finds that erstwhile p53, 1 of the astir important cancer-protecting genes, stops working, cells nutrient excessively overmuch RNA and devour excessive amounts of the gathering blocks needed to transcript their DNA. This shortage disrupts DNA replication, starring to DNA damage, chromosomal instability and large familial changes that tin beforehand crab development.