How RNA molecules influence the development of aggressive leukemia

Researchers astatine the University of Veterinary Medicine Vienna, successful collaboration with the CeMM Research Center for Molecular Medicine and St. Anna Children's Cancer Research, person developed a caller analytical method that reveals which RNA molecules are progressive successful cancer-promoting cellular structures. Using this method, the Vienna-based probe squad identified the RNA molecule Gas5 arsenic an important regulator of NUP98::KDM5A oncogenic condensates, which power cistron enactment successful assertive forms of acute myeloid leukemia (AML). This caller penetration whitethorn supply important starting points for crab probe and improved diligent treatment. The survey was published successful the diary The EMBO Journal.