Immune cells reveal widespread SMN protein loss in spinal muscular atrophy

Spinal muscular atrophy (SMA) is simply a neurodegenerative upset that leads to musculus nonaccomplishment and tin severely impair the mobility of those affected. It is usually caused by a defect successful the SMN1 gene, which is expressed successful each cells of the body. Whether this mutation besides affects the immune strategy remains mostly underexplored. That is precisely what researchers from TWINCORE, the Center for Experimental and Clinical Infection Research, and Hannover Medical School (MHH) person present investigated. Their findings person been published successful the Journal of Clinical Investigation.