Losing TDP-43 protein in microglia disrupts myelin, causing motor deficits in mice

Rosa Chiara Paolicelli's squad astatine the Department of Biomedical Sciences of Unil uncovered a caller relation for the TDP-43 macromolecule successful controlling the relation of microglia, the immune cells of the brain. Their survey shows however the nonaccomplishment of this macromolecule successful microglia whitethorn lend to the improvement of neurological diseases. The findings person been published successful Nature Neuroscience.