Making invisible cancers visible: A new route to turn 'cold' tumors 'hot'

One of the biggest challenges successful crab immunotherapy whitethorn not beryllium that immune cells are excessively weak, but that immoderate tumors springiness them excessively small to see. New probe from Dana-Farber Cancer Institute scientists reveals however cancers carrying mutations successful the p53 tumor-suppressor macromolecule tin fell those mutations from T cells and suggests a therapeutic countermeasure: Change what the crab displays connected its aboveground truthful the immune strategy tin admit the tumor.