Mouse study reveals molecular link between high-fat diets and impaired brain function

The molecular mechanisms linking a high-calorie fare to cognitive impairment stay unclear. Researchers astatine the Institute of Science Tokyo, Japan, investigated this relation successful mice, uncovering that the fare reduced look of the atomic macromolecule PQBP1, disrupting the alternate splicing of genes progressive successful synaptic function. This was associated with synaptic abnormalities and cognitive impairment.