Mutation of the MECP2 gene, the main cause of Rett syndrome, alters pubertal development and sex hormones in mice

A probe squad including unit from the Departament of Biologia Celullar one Biologia Funcional astatine the Universitat of València (UV), the Unitat Predepartamental de Medicina astatine Universitat Jaume I of Castelló (UJI) and Queen Mary University of London (QMUL) has shown that a mutation successful the Mecp2 cistron alters the relation of the hypothalamic-pituitary-gonadal axis, which controls intersexual hormone levels, and delays pubertal improvement successful a rodent exemplary of Rett syndrome.