Restoring inhibitory neuron plasticity may reverse neurodevelopmental disorder symptoms, preclinical study suggests

Some of the symptoms of neurodevelopmental disorders (NDDs), specified arsenic autism spectrum upset and epilepsy, whitethorn effect from dysfunction of definite neurons successful the encephalon and their quality to alteration their properties successful effect to experiences—a process called experience-dependent plasticity. In preclinical probe published successful Nature, a squad led by investigators astatine Mass General Brigham identified genes progressive successful these neurons' plasticity and past demonstrated benefits of overexpressing 1 cardinal gene.