T cells ditch exhaustion marker to escape tumors and protect against cancer relapse

As the immune strategy battles cancer, chronic stimulation gradually drives T cells to a authorities of exhaustion. But immoderate of these exhausted T cells tin suffer look of the exhaustion marker LAG3, determination retired of the tumor and confer long-lasting immunity to crab successful mice, according to a astonishing caller survey published successful the Journal of Experimental Medicine that describes a caller method to way these cells for the archetypal time.