Two protective genetic pathways may converge to reduce Alzheimer's disease risk

Alzheimer's illness is the astir communal signifier of dementia worldwide. Although the APOE ε4 allele is the strongest familial hazard origin for late-onset Alzheimer's disease, not each carriers make dementia, indicating that different familial factors tin modify illness risk. In caller years, PLCG2 has emerged arsenic 1 of the astir important protective genes associated with Alzheimer's disease.