Two ways to read a genome: Body-wide, single-cell atlas maps DNA folding and methylation together

Every compartment successful the quality assemblage carries the aforesaid 3 cardinal letters of DNA, yet a neuron, a bosom musculus compartment and a pancreatic beta compartment each usage that shared codification to bash wholly antithetic jobs. How cells propulsion disconnected this instrumentality comes down to epigenetics—chemical tags and three-dimensional structures that govern which genes are progressive and which enactment silent.